Fig. 1
From: Teriflunomide and monomethylfumarate target HIV-induced neuroinflammation and neurotoxicity
Teri and MMF reduce cytokine secretion of monocyte/microglia co-culture. Treatment of the co-culture of HMC3 microglial cells with HIV vector-transduced monocytoid cells (U937) with Teri or MMF. Shown are three independent experiments performed in triplicates. Significance is observed in comparison to microglia in co-culture with HIV vector transduced monocytoid cells. DMSO was used as a solvent and used in the control condition HIV vector. Data are depicted as mean ± SEM. a, c, and d: Statistical analysis was performed using one-way ANOVA (<0.0001) with Tukey’s multiple comparisons test as post hoc analysis. b No significant difference. ***p < 0.001