Skip to main content
Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Teriflunomide and monomethylfumarate target HIV-induced neuroinflammation and neurotoxicity

Fig. 2

Reduced cytokine secretion in primary microglia co-culture upon treatment with MMF. MMF treatment of primary microglia in co-culture with HIV vector-transduced monocytoid cells reduced the release of CXCL10 and CCL5 (a, b), whereas secretion of CCL2 and IL-6 were not altered (c, d) . Monocytoid cells (U937) were added after transduction (HIV-Vector) or non-transduced (non-transduced) to primary microglia. Transfection reagent was used as additional control. Shown are one to two experiments in duplicates or triplicates. Significant differences are observed in comparison to microglia in co-culture with HIV vector-transduced monocytoid cells (***). Data are presented as mean ± SEM. Statistical analysis was performed using one-way ANOVA (<0.0001) with Tukey’s multiple comparison test as post hoc analysis. *p < 0.05; **p < 0.01; ***p < 0.001

Back to article page