Fig. 7

NK cell depletion does not affect susceptibility in adult mice. a–c LACV-infected adult mice were treated with a rabbit serum or b anti-Asialo GM1 to deplete NK cells as described in the “Methods”. Flow cytometry analysis was used to confirm that treatment with b anti-Asialo GM1, but not a rabbit serum resulted in depletion of NK cells. c NK cell depletion did not significantly affect development of neurological disease. Data are plotted as a survival curve analysis of five rabbit serum-treated and six anti-Asialo GM1-treated mice. Statistical analysis was completed using the Mantel-Cox log-rank test. No statistical difference was observed