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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Interactions between Sirt1 and MAPKs regulate astrocyte activation induced by brain injury in vitro and in vivo

Fig. 5

The effects of inhibitors U0126, SP600125, and SB203580 on ERK, JNK, and p38 activation. a U0126, SP600125, and SB203580 (10 μM) significantly inhibited ERK, JNK, and p38MAPK activation respectively in vitro. n = 6/group, **P < 0.01 vs. the DMSO group. b U0126 (200 μM), SP600125, and SB203580 (100 μM) significantly inhibited ERK, JNK, and p38MAPK activation respectively around the lesion site in vivo. n = 6/group, **P < 0.01 vs. the DMSO group

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Journal of Neuroinflammation

ISSN: 1742-2094