Fig. 7

The neuroprotection in mice pretreated with resveratrol to elevate Sirt1 expression or inhibitors to inhibit MAPK pathway activation. a The mNSS significantly reduced in mice with resveratrol and inhibitor groups. b Beam latency showed that resveratrol and inhibitor groups significantly decreased the time of mice to cross the beam compared to the DMSO group after brain injury. Values are showed as mean ± SEM. n = 6/group, *P < 0.05 vs. the DMSO group