Fig. 6

Clozapine did not alter encephalitogenic capacity of T cells to induce EAE. Passive EAE was induced in mice by injection of MOG-specific cells expanded either in vehicle or clozapine. Disease score of mice (a). Disease burden of mice assessed by area under the curve (b). Shown are the means and SEM of individual mice from three experiments combined (n = 15 mice/group). Mann-Whitney test was used to determine whether disease burden (i.e., AUC) was statistically different between groups