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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury

Fig. 1

LPS/IL-4 induces a mixed phenotype in BMDMs. (a-f) LPS/IL-4 (both 10 ng/ml; 24 h) stimulation significantly increased the production of TNFα (a), IL-6 (b), and Nitrite (b) in BMDMs from WT mice (*** P< 0.001; Student’s t test). LPS/IL-4 increased Arg1 (d) protein expression (representative western immunoblot shown (e)) and YM1 (f) mRNA expression in BMDMs (*** P < 0.001; Student’s t test). All data are expressed as means (±SEM; n = 3)

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Journal of Neuroinflammation

ISSN: 1742-2094