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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Mu-opioid receptor and delta-opioid receptor differentially regulate microglial inflammatory response to control proopiomelanocortin neuronal apoptosis in the hypothalamus: effects of neonatal alcohol

Fig. 4

In vitro dose-response effects of ethanol on cytokine secretion from microglia in primary cultures. Showing the changes in the protein levels of pro-inflammatory cytokines TNF-α (a), IFN-γ (b), IL-1α (c), L-1β (d), IL-6 (e), MIP-3α (f), MCP-1 (g), M-CSF (h), CXCL1 (i), and RANTES (j) and anti-inflammatory cytokines IL-4 (k) and IL-13 (l) in microglial conditioned medium following 24-h treatment with various doses of ethanol (25, 50, 100 mM). Data are represented as mean ± SEM (n = 6). Data of all groups were compared by one-way analysis of variance (ANOVA) and the Newman-Keuls posttest. Differences between groups are shown by lines with p values on the top of bar graphs

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Journal of Neuroinflammation

ISSN: 1742-2094