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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes

Fig. 3

No effect of MW150 on IBA1+ microglia volume. a Representative 3D surface reconstructions of IBA1+ cells generated from confocal microscopic imaging using Imaris software. b Mean volume ± standard deviation (SD) of rendered IBA1 cells is shown for the APP/PS1 KI + veh and APP/PS1 KI + MW150 groups. Data represent mean of 3–4 independent z-stacks from each mouse. (n = 11 KI + veh; n = 14 KI + MW150)

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