TY - JOUR AU - Chen, M. F. AU - Gill, A. J. AU - Kolson, D. L. PY - 2014 DA - 2014// TI - Neuropathogenesis of HIV-associated neurocognitive disorders: roles for immune activation, HIV blipping and viral tropism JO - Curr Opin HIV AIDS VL - 9 UR - https://doi.org/10.1097/COH.0000000000000105 DO - 10.1097/COH.0000000000000105 ID - Chen2014 ER - TY - JOUR AU - Williams, D. W. AU - Veenstra, M. AU - Gaskill, P. J. AU - Morgello, S. AU - Calderon, T. M. AU - Berman, J. W. PY - 2014 DA - 2014// TI - Monocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disorders JO - Curr HIV Res VL - 12 UR - https://doi.org/10.2174/1570162X12666140526114526 DO - 10.2174/1570162X12666140526114526 ID - Williams2014 ER - TY - JOUR AU - McCutchan, J. A. AU - Marquie-Beck, J. A. AU - Fitzsimons, C. A. AU - Letendre, S. L. AU - Ellis, R. J. AU - Heaton, R. K. PY - 2012 DA - 2012// TI - Role of obesity, metabolic variables, and diabetes in HIV-associated neurocognitive disorder JO - Neurology VL - 78 UR - https://doi.org/10.1212/WNL.0b013e3182478d64 DO - 10.1212/WNL.0b013e3182478d64 ID - McCutchan2012 ER - TY - JOUR AU - Lane, R. K. AU - Hilsabeck, T. AU - Rea, S. L. PY - 1847 DA - 1847// TI - The role of mitochondrial dysfunction in age-related diseases JO - Biochim Biophys Acta VL - 2015 ID - Lane1847 ER - TY - JOUR AU - Berdanier, C. D. AU - Everts, H. B. PY - 2001 DA - 2001// TI - Mitochondrial DNA in aging and degenerative disease JO - Mutat Res VL - 475 UR - https://doi.org/10.1016/S0027-5107(01)00068-9 DO - 10.1016/S0027-5107(01)00068-9 ID - Berdanier2001 ER - TY - JOUR AU - Xie, Y. M. AU - Jin, L. AU - Chen, X. J. AU - He, M. N. AU - Wang, Y. AU - Liu, R. PY - 2015 DA - 2015// TI - Quantitative changes in mitochondrial DNA copy number in various tissues of pigs during growth JO - Genet Mol Res GMR VL - 14 UR - https://doi.org/10.4238/2015.March.6.12 DO - 10.4238/2015.March.6.12 ID - Xie2015 ER - TY - JOUR AU - West, A. P. AU - Koblansky, A. A. AU - Ghosh, S. PY - 2006 DA - 2006// TI - Recognition and signaling by toll-like receptors JO - Annu Rev Cell Dev Biol VL - 22 UR - https://doi.org/10.1146/annurev.cellbio.21.122303.115827 DO - 10.1146/annurev.cellbio.21.122303.115827 ID - West2006 ER - TY - JOUR AU - Pinto, M. AU - Moraes, C. T. PY - 1842 DA - 1842// TI - Mitochondrial genome changes and neurodegenerative diseases JO - Biochim Biophys Acta VL - 2014 ID - Pinto1842 ER - TY - JOUR AU - Pinto, M. AU - Moraes, C. T. PY - 2015 DA - 2015// TI - Mechanisms linking mtDNA damage and aging JO - Free Radic Biol Med VL - 85 UR - https://doi.org/10.1016/j.freeradbiomed.2015.05.005 DO - 10.1016/j.freeradbiomed.2015.05.005 ID - Pinto2015 ER - TY - JOUR AU - Var, S. R. AU - Day, T. R. C. AU - Vitomirov, A. AU - Smith, D. M. AU - Soontornniyomkij, V. AU - Moore, D. J. PY - 2016 DA - 2016// TI - Mitochondrial injury and cognitive function in HIV infection and methamphetamine use JO - AIDS Lond Engl VL - 30 UR - https://doi.org/10.1097/QAD.0000000000001027 DO - 10.1097/QAD.0000000000001027 ID - Var2016 ER - TY - JOUR AU - Coskun, P. AU - Wyrembak, J. AU - Schriner, S. E. AU - Chen, H. -. W. AU - Marciniack, C. AU - LaFerla, F. PY - 1820 DA - 1820// TI - A mitochondrial etiology of Alzheimer and Parkinson disease JO - Biochim Biophys Acta BBA - Gen Subj VL - 2012 ID - Coskun1820 ER - TY - JOUR AU - Walko, T. D. AU - Bola, R. A. AU - Hong, J. D. AU - Au, A. K. AU - Bell, M. J. AU - Kochanek, P. M. PY - 2014 DA - 2014// TI - Cerebrospinal fluid mitochondrial DNA: a novel DAMP in pediatric traumatic brain injury JO - Shock VL - 41 UR - https://doi.org/10.1097/SHK.0000000000000160 DO - 10.1097/SHK.0000000000000160 ID - Walko2014 ER - TY - JOUR AU - Podlesniy, P. AU - Figueiro-Silva, J. AU - Llado, A. AU - Antonell, A. AU - Sanchez-Valle, R. AU - Alcolea, D. PY - 2013 DA - 2013// TI - Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease JO - Ann Neurol VL - 74 UR - https://doi.org/10.1002/ana.23955 DO - 10.1002/ana.23955 ID - Podlesniy2013 ER - TY - JOUR AU - Pyle, A. AU - Brennan, R. AU - Kurzawa-Akanbi, M. AU - Yarnall, A. AU - Thouin, A. AU - Mollenhauer, B. PY - 2015 DA - 2015// TI - Reduced cerebrospinal fluid mitochondrial DNA is a biomarker for early-stage Parkinson’s disease JO - Ann Neurol VL - 78 UR - https://doi.org/10.1002/ana.24515 DO - 10.1002/ana.24515 ID - Pyle2015 ER - TY - JOUR AU - Crespo, Â. C. AU - Silva, B. AU - Marques, L. AU - Marcelino, E. AU - Maruta, C. AU - Costa, S. PY - 2014 DA - 2014// TI - Genetic and biochemical markers in patients with Alzheimer’s disease support a concerted systemic iron homeostasis dysregulation JO - Neurobiol Aging VL - 35 UR - https://doi.org/10.1016/j.neurobiolaging.2013.10.078 DO - 10.1016/j.neurobiolaging.2013.10.078 ID - Crespo2014 ER - TY - JOUR AU - Medeiros, M. S. AU - Schumacher-Schuh, A. AU - Cardoso, A. M. AU - Bochi, G. V. AU - Baldissarelli, J. AU - Kegler, A. PY - 2016 DA - 2016// TI - Iron and oxidative stress in Parkinson’s disease: an observational study of injury biomarkers JO - PLoS ONE VL - 11 UR - https://doi.org/10.1371/journal.pone.0146129 DO - 10.1371/journal.pone.0146129 ID - Medeiros2016 ER - TY - JOUR AU - Ringman, J. M. AU - Schulman, H. AU - Becker, C. AU - Jones, T. AU - Bai, Y. AU - Immermann, F. PY - 2012 DA - 2012// TI - Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations JO - Arch Neurol VL - 69 UR - https://doi.org/10.1001/archneurol.2011.642 DO - 10.1001/archneurol.2011.642 ID - Ringman2012 ER - TY - JOUR AU - Rensvold, J. W. AU - Ong, S. -. E. AU - Jeevananthan, A. AU - Carr, S. A. AU - Mootha, V. K. AU - Pagliarini, D. J. PY - 2013 DA - 2013// TI - Complementary RNA and protein profiling identifies iron as a key regulator of mitochondrial biogenesis JO - Cell Rep VL - 3 UR - https://doi.org/10.1016/j.celrep.2012.11.029 DO - 10.1016/j.celrep.2012.11.029 ID - Rensvold2013 ER - TY - JOUR AU - Allen, G. F. G. AU - Toth, R. AU - James, J. AU - Ganley, I. G. PY - 2013 DA - 2013// TI - Loss of iron triggers PINK1/Parkin-independent mitophagy JO - EMBO Rep VL - 14 UR - https://doi.org/10.1038/embor.2013.168 DO - 10.1038/embor.2013.168 ID - Allen2013 ER - TY - JOUR AU - Andersen, H. H. AU - Johnsen, K. B. AU - Moos, T. PY - 2014 DA - 2014// TI - Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration JO - Cell Mol Life Sci CMLS VL - 71 UR - https://doi.org/10.1007/s00018-013-1509-8 DO - 10.1007/s00018-013-1509-8 ID - Andersen2014 ER - TY - JOUR AU - Wen, X. AU - Wu, J. AU - Wang, F. AU - Liu, B. AU - Huang, C. AU - Wei, Y. PY - 2013 DA - 2013// TI - Deconvoluting the role of reactive oxygen species and autophagy in human diseases JO - Free Radic Biol Med VL - 65 UR - https://doi.org/10.1016/j.freeradbiomed.2013.07.013 DO - 10.1016/j.freeradbiomed.2013.07.013 ID - Wen2013 ER - TY - JOUR AU - Schiavi, A. AU - Maglioni, S. AU - Palikaras, K. AU - Shaik, A. AU - Strappazzon, F. AU - Brinkmann, V. PY - 2015 DA - 2015// TI - Iron-starvation-induced mitophagy mediates lifespan extension upon mitochondrial stress in C. elegans JO - Curr Biol CB VL - 25 UR - https://doi.org/10.1016/j.cub.2015.05.059 DO - 10.1016/j.cub.2015.05.059 ID - Schiavi2015 ER - TY - JOUR AU - Heaton, R. K. AU - Clifford, D. B. AU - Franklin, D. R. AU - Woods, S. P. AU - Ake, C. AU - Vaida, F. PY - 2010 DA - 2010// TI - HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study JO - Neurology VL - 75 UR - https://doi.org/10.1212/WNL.0b013e318200d727 DO - 10.1212/WNL.0b013e318200d727 ID - Heaton2010 ER - TY - JOUR AU - Heaton, R. K. AU - Franklin, D. R. AU - Deutsch, R. AU - Letendre, S. AU - Ellis, R. J. AU - Casaletto, K. PY - 2015 DA - 2015// TI - Neurocognitive change in the era of HIV combination antiretroviral therapy: the longitudinal CHARTER study JO - Clin Infect Dis Off Publ Infect Dis Soc Am VL - 60 UR - https://doi.org/10.1093/cid/ciu862 DO - 10.1093/cid/ciu862 ID - Heaton2015 ER - TY - JOUR AU - Antinori, A. AU - Arendt, G. AU - Becker, J. T. AU - Brew, B. J. AU - Byrd, D. A. AU - Cherner, M. PY - 2007 DA - 2007// TI - Updated research nosology for HIV-associated neurocognitive disorders JO - Neurology VL - 69 UR - https://doi.org/10.1212/01.WNL.0000287431.88658.8b DO - 10.1212/01.WNL.0000287431.88658.8b ID - Antinori2007 ER - TY - JOUR AU - Blackstone, K. AU - Moore, D. J. AU - Franklin, D. R. AU - Clifford, D. B. AU - Collier, A. C. AU - Marra, C. M. PY - 2012 DA - 2012// TI - Defining neurocognitive impairment in HIV: deficit scores versus clinical ratings JO - Clin Neuropsychol VL - 26 UR - https://doi.org/10.1080/13854046.2012.694479 DO - 10.1080/13854046.2012.694479 ID - Blackstone2012 ER - TY - JOUR AU - Ellis, R. J. AU - Hsia, K. AU - Spector, S. A. AU - Nelson, J. A. AU - Heaton, R. K. AU - Wallace, M. R. PY - 1997 DA - 1997// TI - Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center Group JO - Ann Neurol VL - 42 UR - https://doi.org/10.1002/ana.410420503 DO - 10.1002/ana.410420503 ID - Ellis1997 ER - TY - JOUR AU - Ellis, R. J. AU - Badiee, J. AU - Vaida, F. AU - Letendre, S. AU - Heaton, R. K. AU - Clifford, D. PY - 2011 DA - 2011// TI - CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy JO - AIDS Lond Engl VL - 25 UR - https://doi.org/10.1097/QAD.0b013e32834a40cd DO - 10.1097/QAD.0b013e32834a40cd ID - Ellis2011 ER - TY - BOOK PY - 2014 DA - 2014// TI - R: A language and environment for statistical computing PB - R Foundation for Statistical Computing CY - Vienna ID - ref29 ER - TY - JOUR AU - Arnalich, F. AU - Codoceo, R. AU - López-Collazo, E. AU - Montiel, C. PY - 2012 DA - 2012// TI - Circulating cell-free mitochondrial DNA: a better early prognostic marker in patients with out-of-hospital cardiac arrest JO - Resuscitation VL - 83 UR - https://doi.org/10.1016/j.resuscitation.2012.03.032 DO - 10.1016/j.resuscitation.2012.03.032 ID - Arnalich2012 ER - TY - JOUR AU - Alvarado-Vásquez, N. PY - 2015 DA - 2015// TI - Circulating cell-free mitochondrial DNA as the probable inducer of early endothelial dysfunction in the prediabetic patient JO - Exp Gerontol VL - 69 UR - https://doi.org/10.1016/j.exger.2015.05.010 DO - 10.1016/j.exger.2015.05.010 ID - Alvarado-Vásquez2015 ER - TY - JOUR AU - Lu, H. AU - Busch, J. AU - Jung, M. AU - Rabenhorst, S. AU - Ralla, B. AU - Kilic, E. PY - 2016 DA - 2016// TI - Diagnostic and prognostic potential of circulating cell-free genomic and mitochondrial DNA fragments in clear cell renal cell carcinoma patients JO - Clin Chim Acta Int J Clin Chem VL - 452 UR - https://doi.org/10.1016/j.cca.2015.11.009 DO - 10.1016/j.cca.2015.11.009 ID - Lu2016 ER - TY - JOUR AU - Yu, M. PY - 2012 DA - 2012// TI - Circulating cell-free mitochondrial DNA as a novel cancer biomarker: opportunities and challenges JO - Mitochondrial DNA VL - 23 UR - https://doi.org/10.3109/19401736.2012.696625 DO - 10.3109/19401736.2012.696625 ID - Yu2012 ER - TY - JOUR AU - Liu, J. AU - Cai, X. AU - Xie, L. AU - Tang, Y. AU - Cheng, J. AU - Wang, J. PY - 2015 DA - 2015// TI - Circulating cell free mitochondrial DNA is a biomarker in the development of coronary heart disease in the patients with type 2 diabetes JO - Clin Lab VL - 61 ID - Liu2015 ER - TY - JOUR AU - Sudakov, N. P. AU - Popkova, T. P. AU - Katyshev, A. I. AU - Goldberg, O. A. AU - Nikiforov, S. B. AU - Pushkarev, B. G. PY - 2015 DA - 2015// TI - Level of Blood Cell-Free Circulating Mitochondrial DNA as a Novel Biomarker of Acute Myocardial Ischemia JO - Biochem VL - 80 ID - Sudakov2015 ER - TY - STD TI - Pérez-Santiago J, Schrier RD, de Oliveira MF, Gianella S, Var SR, Day TRC, et al. Cell-free mitochondrial DNA in CSF is associated with early viral rebound, inflammation, and severity of neurocognitive deficits in HIV infection. J Neurovirol. 2015;22(2):191-200. ID - ref36 ER - TY - JOUR AU - Kallianpur, A. R. AU - Levine, A. J. PY - 2014 DA - 2014// TI - Host genetic factors predisposing to HIV-associated neurocognitive disorder JO - Curr HIV/AIDS Rep VL - 11 UR - https://doi.org/10.1007/s11904-014-0222-z DO - 10.1007/s11904-014-0222-z ID - Kallianpur2014 ER - TY - JOUR AU - Kallianpur, A. R. AU - Wang, Q. AU - Jia, P. AU - Hulgan, T. AU - Zhao, Z. AU - Letendre, S. L. PY - 2016 DA - 2016// TI - Anemia and red blood cell indices predict HIV-associated neurocognitive impairment in the highly active antiretroviral therapy era JO - J Infect Dis VL - 213 UR - https://doi.org/10.1093/infdis/jiv754 DO - 10.1093/infdis/jiv754 ID - Kallianpur2016 ER - TY - STD TI - Jayson GC, Kerbel R, Ellis LM, Harris AL. Antiangiogenic therapy in oncology: current status and future directions. Lancet Lond Engl. 2016;388(10043):518-29. ID - ref39 ER - TY - JOUR AU - Lowndes, S. A. AU - Harris, A. L. PY - 2004 DA - 2004// TI - Copper chelation as an antiangiogenic therapy JO - Oncol Res VL - 14 ID - Lowndes2004 ER - TY - STD TI - Burkhart A, Skjørringe T, Johnsen KB, Siupka P, Thomsen LB, Nielsen MS, et al. Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier. Mol Neurobiol. 2016;53(10):7237-53. ID - ref41 ER - TY - STD TI - Arber CE, Li A, Houlden H, Wray S. Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories. Neuropathol Appl Neurobiol. 2015;42(3):220-41. ID - ref42 ER - TY - JOUR AU - Kumar, S. AU - Guru, S. K. AU - Pathania, A. S. AU - Kumar, A. AU - Bhushan, S. AU - Malik, F. PY - 2013 DA - 2013// TI - Autophagy triggered by magnolol derivative negatively regulates angiogenesis JO - Cell Death Dis VL - 4 UR - https://doi.org/10.1038/cddis.2013.399 DO - 10.1038/cddis.2013.399 ID - Kumar2013 ER - TY - JOUR AU - Simpson, I. A. AU - Ponnuru, P. AU - Klinger, M. E. AU - Myers, R. L. AU - Devraj, K. AU - Coe, C. L. PY - 2015 DA - 2015// TI - A novel model for brain iron uptake: introducing the concept of regulation JO - J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab VL - 35 UR - https://doi.org/10.1038/jcbfm.2014.168 DO - 10.1038/jcbfm.2014.168 ID - Simpson2015 ER - TY - JOUR AU - Ivatt, R. M. AU - Whitworth, A. J. PY - 2014 DA - 2014// TI - The many faces of mitophagy JO - EMBO Rep VL - 15 UR - https://doi.org/10.1002/embr.201338224 DO - 10.1002/embr.201338224 ID - Ivatt2014 ER - TY - JOUR AU - Ho, E. L. AU - Ronquillo, R. AU - Altmeppen, H. AU - Spudich, S. S. AU - Price, R. W. AU - Sinclair, E. PY - 2013 DA - 2013// TI - Cellular composition of cerebrospinal fluid in HIV-1 infected and uninfected subjects JO - PLoS ONE VL - 8 UR - https://doi.org/10.1371/journal.pone.0066188 DO - 10.1371/journal.pone.0066188 ID - Ho2013 ER - TY - JOUR AU - Tiraboschi, J. M. AU - Muñoz-Moreno, J. A. AU - Puertas, M. C. AU - Alonso-Villaverde, C. AU - Prats, A. AU - Ferrer, E. PY - 2015 DA - 2015// TI - Viral and inflammatory markers in cerebrospinal fluid of patients with HIV-1-associated neurocognitive impairment during antiretroviral treatment switch JO - HIV Med VL - 16 UR - https://doi.org/10.1111/hiv.12243 DO - 10.1111/hiv.12243 ID - Tiraboschi2015 ER - TY - JOUR AU - Marra, C. M. AU - Maxwell, C. L. AU - Collier, A. C. AU - Robertson, K. R. AU - Imrie, A. PY - 2007 DA - 2007// TI - Interpreting cerebrospinal fluid pleocytosis in HIV in the era of potent antiretroviral therapy JO - BMC Infect Dis VL - 7 UR - https://doi.org/10.1186/1471-2334-7-37 DO - 10.1186/1471-2334-7-37 ID - Marra2007 ER - TY - JOUR AU - McIlroy, D. J. AU - Jarnicki, A. G. AU - Au, G. G. AU - Lott, N. AU - Smith, D. W. AU - Hansbro, P. M. PY - 2014 DA - 2014// TI - Mitochondrial DNA neutrophil extracellular traps are formed after trauma and subsequent surgery JO - J Crit Care VL - 29 UR - https://doi.org/10.1016/j.jcrc.2014.07.013 DO - 10.1016/j.jcrc.2014.07.013 ID - McIlroy2014 ER - TY - JOUR AU - Davis, C. O. AU - Kim, K. -. Y. AU - Bushong, E. A. AU - Mills, E. A. AU - Boassa, D. AU - Shih, T. PY - 2014 DA - 2014// TI - Transcellular degradation of axonal mitochondria JO - Proc Natl Acad Sci U S A VL - 111 UR - https://doi.org/10.1073/pnas.1404651111 DO - 10.1073/pnas.1404651111 ID - Davis2014 ER - TY - STD TI - Borgmann K, Ghorpade A. HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads. Front Microbiol. 2015;6:1143. ID - ref51 ER - TY - JOUR AU - Dickens, A. M. AU - Anthony, D. C. AU - Deutsch, R. AU - Mielke, M. M. AU - Claridge, T. D. W. AU - Grant, I. PY - 2015 DA - 2015// TI - Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients JO - AIDS Lond Engl VL - 29 ID - Dickens2015 ER - TY - JOUR AU - Zhao, L. AU - Hadziahmetovic, M. AU - Wang, C. AU - Xu, X. AU - Song, Y. AU - Jinnah, H. A. PY - 2015 DA - 2015// TI - Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone JO - J Neurochem VL - 135 UR - https://doi.org/10.1111/jnc.13292 DO - 10.1111/jnc.13292 ID - Zhao2015 ER - TY - JOUR AU - Singh, N. AU - Haldar, S. AU - Tripathi, A. K. AU - Horback, K. AU - Wong, J. AU - Sharma, D. PY - 2014 DA - 2014// TI - Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities JO - Antioxid Redox Signal VL - 20 UR - https://doi.org/10.1089/ars.2012.4931 DO - 10.1089/ars.2012.4931 ID - Singh2014 ER -