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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Diffusion MRI quantifies early axonal loss in the presence of nerve swelling

Fig. 6

Regression of SMI-31, MBP, SMI-312, DAPI counts, and DBSI-derived λǁ (a), λ (b), fiber fraction (c), and restricted fraction (d) suggested DBSI measurements were able to reflect specific pathologies in the optic nerves of EAE mice, respectively. The regression of DBSI-derived axon volume correlated with SMI-312 area (e, in mm2). In contrast to SMI-312 area estimated as ratio of positive area over the total nerve cross-sectional area (%, c), SMI-312 area in square millimeter reflects the extent of total axons without the dilution effect of inflammation. SE standard error

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