Skip to main content
Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring

Fig. 2

Gestational diabetes mellitus reduces hippocampal synaptic protein expression and deranges CA1 neuronal layer, when combined with postnatal HFS diet. a, b, e Micrographs of 15-week-old rat hippocampus with NeuN and synaptophysin. a–d NeuN staining did not show clear reduction in neuronal numbers, but changes in CA1 pyramidal neuronal layer thickness and density were evident. e, f Hippocampal CA1 area in GDM offspring had decreased synaptophysin expression suggesting decreased synaptic terminal integrity. *p ≤ 0.05 compared to lean, n = 6

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094