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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: The PD-1: PD-L1 pathway promotes development of brain-resident memory T cells following acute viral encephalitis

Fig. 7

CD103+ and CD69+ CD8 T cells express Bcl-2 within the infected brain. Cells were isolated from the brains of MCMV-infected WT and PD-L1 KO mice at 30 dpi and evaluated for the expression of the pro-survival molecule Bcl-2 on CD103+CD69+-gated CD8+ T cells. a Representative flow cytometric analysis of intracellular expression of Bcl-2 expression in CD103+CD69+-gated CD8+ T cells among WT and PD-L1 KO animals at 30 dpi. b Pooled data present the percentage (mean ± SD) of Bcl-2 expression on CD103+CD69+ cells among different groups of mice at the indicated time point (n = 3 from both groups). *p < 0.01 WT versus PD-L1 KO for Bcl-2 expression in CD69+CD103+ cells at 30 dpi

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