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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Adiponectin levels in the serum and cerebrospinal fluid of amyotrophic lateral sclerosis patients: possible influence on neuroinflammation?

Fig. 5

Hypothetical role of gender-specific APN alterations in ALS. Both genders share the same pathological features but opposite serum APN levels (a, b). Therefore, different biological cascades (c) may induce disruption of APN signalling in ALS patients and enhance neuroinflammation and motor neuron degeneration (d), so a clear dissection of their single contribution deserves to be deeply investigated

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