Fig. 5
From: Lack of interleukin-13 receptor α1 delays the loss of dopaminergic neurons during chronic stress
IL-13Rα1 contributes to dopaminergic neuronal loss during chronic stress. a Representative images of labeling of TH+ neurons using wild-type Il13ra Y/+ and knock-out Il13ra Y/− mouse brains from control mice and at different time points in the RS paradigm. b Histograms showing the number of TH+ neurons in the Il13ra Y/+and Il13ra Y/− in the SNc under control conditions, RS 8 h, after 16 weeks of RS, and after 16 weeks of RS plus 4 weeks of rest. c Representative images of cresyl violet labeling (Nissl staining) cells used in adjacent section to the ones assessed by TH staining. d Histograms showing the average cell count of CV+ cells in the Il13ra Y/+ and Il13ra Y/− in the SNc under control conditions, RS 8 h, after 16 weeks of RS, and after 16 weeks of RS plus 4 weeks of rest. (*p < 0.05, ***p < 0.001 compared to control condition, n = 4–6; scale bars: 200 μm in A, C)