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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Early strong intrathecal inflammation in cerebellar type multiple system atrophy by cerebrospinal fluid cytokine/chemokine profiles: a case control study

Fig. 5

Correlations between cytokine levels and MRI measurements of each part of the hindbrain. a Heatmap analysis of correlations between cytokine levels and MRI measurements. R values of Pearson’s correlation coefficient analysis are divided into quintiles, and p values calculated using one-way ANOVA are indicated as a heatmap. Among the 27 cytokines studied, IL-5, IL-6, IL-9, IL-12, IL-13, PDGF-bb, MIP-1α, and GM-CSF showed significant positive correlations with MRI measurements. b Linear regression analysis between cytokine levels and MRI measurements for cytokines that showed significant correlations. R values and p values calculated using Pearson’s correlation coefficient analysis are indicated on each dot plot. *p < 0.05, **p < 0.01. GM-CSF: granulocyte-macrophage colony-stimulating factor, IL: interleukin, MIP: macrophage inflammatory protein, MRI: magnetic resonance imaging, PDGF: platelet-derived growth factor

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