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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Fingolimod attenuates experimental autoimmune neuritis and contributes to Schwann cell-mediated axonal protection

Fig. 1

Fingolimod ameliorates disease course in EAN. Clinical score of immunized rats treated with different concentrations of fingolimod until complete decline of symptoms (a) or till near maximum disease course (b). After induction of EAN on day 0, animals were treated daily and orally with different concentrations of fingolimod. Concentrations of 0.1 mg/kg fingolimod and upwards prevented development of clinical symptoms. One to two independent experiments with four animals per group were performed. Statistical analysis and p value were obtained by calculating the area under the curve of each condition. Comparison of AUC was done using one-way ANOVA combined with Tukey’s multiple comparisons test; ***p < 0.001

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