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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors

Fig. 1

CUS increases ATP in microdialysates from the hippocampus but not levels of P2X7 receptor protein in the hippocampus. a Immunofluorescence staining of hippocampal sections from normal rats. P2X7R (green), Iba-1 (red), GFAP (red), DAPI (blue); scale bar, 50 μm. b Microdialysis samples were collected from the hippocampus of rats exposed to 1, 2, and 3 weeks of CUS, respectively, and analyzed for levels of ATP (n = 4 per group). c Western blots of P2X7R in the hippocampus from rats exposed to 1, 2, and 3 weeks of CUS, respectively. GAPDH was used as a loading control and the graphs represent the mean ± SEM (n = 4 per group). ## p < 0.01 compared to normal rats at the same time point

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