Fig. 3

Expression of TXNIP and inflammatory factors after RES and TXNIP siRNA treatment. Representative Western blot of TXNIP, TRX1, NLRP3, cleaved Caspase-1 (CC1) and cleaved IL-1β (a, d). Densitometric quantification of protein band optical densities for TXNIP, TRX1, NLRP3, CC1 and cleaved IL-1β (b, c, e, f, and Additional file 1: Figure S1 and Additional file 2: Figure S2). The expression of TXNIP and inflammatory factors was reduced by RES and TXNIP siRNA treatment. Results were analysed using the Fusion system (fx 7 Spectra, Vilber, France). Results are expressed as a percentage of the values for β-actin. *p < 0.05 vs. sham; ^# p < 0.05 vs. SAH + NS; ^@ p < 0.05 vs SAH + control siRNA. TXNIP thioredoxin-interacting protein, TRX1 thioredoxin 1, NLRP3 inflammasome nod-like receptor protein 3 inflammasome, IL-1β interleukin-1β, CC1 cleaved Caspase-1, siRNA small interfering RNA, RES resveratrol, NS normal saline