Fig. 4
From: Acute neuroinflammation induces AIS structural plasticity in a NOX2-dependent manner
Treatment with Didox alters microglial NOX2 levels. a–d Microglia, visualized by Iba-1 immunolabeling, display enhanced NOX2 immunoreactivity in LPS 24 h (b’) and LPS 1 week (c’) mice compared to saline controls (a’). Anti-inflammatory Didox treatment decreases microglial NOX2 immunoreactivity (d’) to saline control levels (a’). Scale bar = 30 μM. e The mean percentage ± SEM of NOX2-positive microglia in saline-, LPS-treated, and LPS + Didox mice. An asterisk indicates significant difference (p < 0.05) from saline, and a ¥ indicates a difference between treatment groups