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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: B cells do not have a major pathophysiologic role in acute ischemic stroke in mice

Fig. 1

Pharmacologic prestroke B cell depletion does not alter stroke outcome in a transient middle cerebral artery occlusion (tMCAO) model. a Left, representative 2,3,5-triphenyltetrazolium chloride stains of three corresponding brain sections of an IgG-treated C57BL/6 mouse (IgG) and a C57BL/6 mouse at day 1 after stroke, treated with a specific antibody against CD20 1 day before 60-min tMCAO. a Right, infarct volumes are similar (n = 8/group) between the two treatment groups (unpaired, two-tailed Student’s t test). b B cell depletion does not improve functional outcome on day 1 after tMCAO (n = 8/group) as assessed by the grip test (left) and Bederson score (right), Mann–Whitney test

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