Fig. 5From: Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune systemCtsE is downregulated in bone marrow and bone marrow-derived macrophages from V30M mice. Histogram represents CtsE mRNA levels in the a bone marrow and b bone marrow-derived macrophages from WT and V30M mice, normalized against Gapdh. c Western blots performed with macrophage lysates show both pro and activated CtsE in a much lesser extent in V30M mice. d Confocal microscopy denote a different staining pattern for CtsE in V30M macrophages when compared with WT (×20 magnification). Results were corroborated with three independent cell experimentsBack to article page