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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system

Fig. 5

CtsE is downregulated in bone marrow and bone marrow-derived macrophages from V30M mice. Histogram represents CtsE mRNA levels in the a bone marrow and b bone marrow-derived macrophages from WT and V30M mice, normalized against Gapdh. c Western blots performed with macrophage lysates show both pro and activated CtsE in a much lesser extent in V30M mice. d Confocal microscopy denote a different staining pattern for CtsE in V30M macrophages when compared with WT (×20 magnification). Results were corroborated with three independent cell experiments

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