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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies

Fig. 1

YKL-40 expression pattern in human brain tissue from an AD patient and a healthy control. Representative images of double immunofluorescence performed with YKL-40 (red) and three different cellular markers, GFAP (astroglial, green), MAP2 (neuronal, green) and IBA-1 (microglial, green). Nuclei are marked in blue. a–h YKL-40 immunoreactivity was detected in the cytoplasm of GFAP+ cells (asterisk), indicating an astroglial origin. i–p No colocalization was observed between YKL-40 and the neuronal marker, MAP2 or (q–x) with the microglial marker, IBA-1. Scale bar = 20 μm

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Journal of Neuroinflammation

ISSN: 1742-2094