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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement

Fig. 6

Histopathology of spinal cords from B4-Crry treated showed reduced spread of lesion 72 h after SCI. a H&E stained coronal and sagittal sections from epicenter of contusion injury after B4-Crry or PBS treatment. Representative images, n = 6. b, c Quantification of lesion and hemorrhage. Lesion size and hemorrhaged area were determined from step sections obtained across 1-mm distance from the epicenter and expressed as percentage of total area of each section analyzed. Mean ± SE, **p < 0.01, ***p < 0.001, n = 6.

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