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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Isoliquiritigenin alleviates early brain injury after experimental intracerebral hemorrhage via suppressing ROS- and/or NF-κB-mediated NLRP3 inflammasome activation by promoting Nrf2 antioxidant pathway

Fig. 2

Effects of ILG on BBB disruption and the number of degenerating neuron following ICH (a-d). ILG administration at the dosages of 20 and 40 mg/kg significantly alleviated the extravasation of EB dyes and the number of FJC+ staining cells. Macroscopic images of brains with extravasated EB dyes (a) and corresponding quantitative analyses (b) (n = 6 rats/group). Typical microscopic images for FJC+ staining cells from injury brain tissues (c) and quantitative analyses of the number of FJC+ staining cells (d) (n = 6 rats/group). Scale bar = 20 μm. Values are reported as means ± SD. **p < 0.01

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Journal of Neuroinflammation

ISSN: 1742-2094