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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Evidence for an early innate immune response in the motor cortex of ALS

Fig. 5

Number of MCP1+ cells increases during disease progression in the spinal cord of MCP1-CCR2-hSOD1G93A mice. ah Graphs represent average number of MCP1+ cells numbers per section ± SEM in MCP1-CCR2-WT mice (blue columns) and MCP1-CCR2-hSOD1G93A triple transgenic mice (red column) in the cervical (ad) and lumbar spinal cord (eh) at the pre-symptomatic (P30), early symptomatic (P60), symptomatic (P90), and end stage (P120). il Representative drawings showing the relative location of MCP1+ cells in the three regions of the lumbar spinal cord studied. Abbreviations: CST corticospinal tract, VGM ventral grey matter, DGM dorsal grey matter. *p < 0.05, **p < 0.01, ***p < 0.01; MCP1-CCR2-WT mice vs. MCP1-CCR2-hSOD1G93A triple transgenic mice

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