Fig. 3

The concentrations of MIF, TNF-α, and IL-1β in serum on admission to hospital. The concentration of MIF (a), TNF-α (b), and IL-1β (c) in serum on admission to hospital in patients with tick-borne encephalitis (TBE—empty boxes; n = 36), other lymphocytic meningitis (non-TBE—light-filled boxes; n = 7) and controls (c dark-filled boxes; n = 6). Shown are median (horizontal line), quartiles (box), and minimum/maximum values (whiskers). The thick horizontal line at the bottom denotes the lower detection limit in b and c. ***significant difference in comparison with controls (p < 0.001); **significant difference in comparison with controls (p < 0.01); *significant difference in comparison with controls (p < 0.05); the difference between the TBE group and controls not reaching the level of the statistical significance is shown directly in b