Fig. 8

The serum concentrations of MIF and TNFα dependent on TLR3 genotypes. Concentrations of MIF (a) and TNFα (b) in serum of TBE patients with TT (n = 16), TA (n = 14), and AA genotype (n = 5) in rs5743305 locus and in healthy controls (C, n = 6). Shown are median (line), quartiles (box), and minimum/maximum values (whiskers). The thick horizontal line denotes the detection limit in b. *increased in comparison with controls, p < 0.05; **increased in comparison with controls, p < 0.01; ***increased in comparison with controls, p < 0.001; ^tendency for a lower concentration in AA in comparison with TT/TA with p = 0.06