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Table 3 The distribution of the TLR3 and MIF genotypes in patients with tick-borne encephalitis

From: The increased concentration of macrophage migration inhibitory factor in serum and cerebrospinal fluid of patients with tick-borne encephalitis

Gene

TLR3

MIF

SNP

rs3775291

rs5743305

rs755622

Genotype

CC

TC

TT

TT

AT

AA

GG

GC

CC

M (n = 46)

4 (9%)

14 (30%)

28 (61%)

17 (37%)

24 (52%)

5 (11%)

26 (57%)

17 (37%)

3 (7%)*

ME (n = 57)

4 (7%)

26 (46%)

27 (47%)

28 (49%)

24 (42%)

5 (9%)

42 (74%)

15 (26%)

0 (0%)*

MEM (n = 5)

0 (0%)

3 (60%)

2 (40%)

1 (20%)

3 (60%)

1 (20%)

3 (60%)

2 (40%)

0 (0%)*

  1. The genotypes of the studied single nucleotide polymorphisms (SNPs) in TLR3 and MIF in the groups of patients with different clinical forms of the tick-borne encephalitis virus infection
  2. M meningitis, ME meningoencephalitis, MEM meningoencephalomyelitis
  3. *Statistically significant difference between M and ME/MEM, p < 0.05