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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Interleukin-1 receptor type 1 is overexpressed in neurons but not in glial cells within the rat superficial spinal dorsal horn in complete Freund adjuvant-induced inflammatory pain

Fig. 2

Mechanical withdrawal threshold of rats during the course of CFA-induced inflammation of the hind paw. The histogram shows the mechanical withdrawal threshold (MWT) on both hind limbs of control animals and animals receiving CFA injection into the right hind paw. Note that MWT values appeared to be remarkably stable throughout the entire length of the experimental period in control animals and in the untreated left hind paw of animals receiving CFA injection into the right hind paw. However, CFA injection resulted in a substantial drop in MWT values in the right hind paw of experimental animals which peaked at post-injection days 2 and 3 and returned back to normal values by post-injection day 11. Data are shown as mean ± SEM

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