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Table 2 List of genes that showed statistically significant changes in tissue samples obtained from the spinal dorsal horn of CFA-injected animals ipsilateral to the CFA injection at post-injection day 3 (at the peak of mechanical allodynia)

From: Interleukin-1 receptor type 1 is overexpressed in neurons but not in glial cells within the rat superficial spinal dorsal horn in complete Freund adjuvant-induced inflammatory pain

Gene symbol Gene name ΔCt control ΔCt treated Fold change 2-ΔΔCt p value
Faah fatty acid amid hydrolase 6.4 ± 0.01 6.7 ± 0.1 0.78 0.0368
Gria2 ionotropic glutamate receptor, AMPA2 3.0 ± 0.24 3.3 ± 0.06 0.77 0.0447
il1r1 interleukin 1 receptor 1 14.7 ± 0.001 12.1 ± 0.002 6.02 0.0002
Nape-pld N-acyl-phosphatidylethanolamine-hydrolising phospholipase D 7.0 ± 0.06 6.9 ± 0.17 1.11 0.0016
  1. Values obtained from CFA-injected animals were compared to values obtained from control animals. Note that we observed a highly significant, approximately six times increase in the quantity of IL-1R1 receptor mRNA in the experimental animals