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Table 3 Comparison of chemokines and cytokines, including correlations, in CSF and serum of HSE and HSM patients

From: CXCL11 production in cerebrospinal fluid distinguishes herpes simplex meningitis from herpes simplex encephalitis

  Factor CSF/serum p CSF vs. serum Correlation HSE Correlation HSM
Cytokine HSE HSM HSE HSM r p r p
CCL1 0.5 0.4 0.016 0.0078 0.3 0.50 0.4 0.30
CCL2 3 5 0.016 0.0078 −0.5 0.20 −0.4 0.36
CCL3 1 2 0.15 0.0078 0.2 0.66 0.4 0.39
CCL7 0.2 0.7 0.023 0.055 −0.6 0.15 0.8 0.015
CCL8 0.7 23 0.74 0.0078 −0.2 0.66 −0.1 0.75
CCL11 0.1 0.2 0.0078 0.0078 0.3 0.50 0.3 0.50
CCL13 0.03 0.2 0.0078 0.039 −0.1 0.84 0.1 0.88
CCL15 0.05 0.1 0.0078 0.0078 0.5 0.27 0.1 0.79
CCL17 0.1 0.2 0.0078 0.0078 0.2 0.66 −0.1 0.79
CCL19 0.3 0.4 0.039 0.11 −0.1 0.84 0.7 0.069
CCL20 0.07 0.5 0.0078 0.023 0.0 0.93 0.7 0.070
CCL21 0.1 0.2 0.0078 0.0078 0.4 0.30 0.3 0.43
CCL22 0.09 0.05 0.0078 0.0078 0.1 0.79 0.2 0.66
CCL23 0.05 0.04 0.0078 0.0078 0.2 0.70 −0.1 0.87
CCL24 0.03 0.04 0.0078 0.0078 0.5 0.24 0.8 0.028
CCL25 0.1 0.3 0.0078 0.0078 −0.3 0.54 0.3 0.54
CCL26 0.2 0.3 0.0078 0.0078 0.2 0.70 0.5 0.24
CCL27 0.01 0.01 0.0078 0.0078 0.0 0.93 0.1 0.88
CX3CL1 0.7 0.8 0.016 0.15 0.1 0.75 0.5 0.22
CXCL1 0.2 0.6 0.31 0.25 −0.5 0.20 0.3 0.50
CXCL2 0.01 0.03 0.0078 0.0078 −0.3 0.46 0.5 0.26
CXCL5 0.1 0.4 0.0078 0.016 −0.1 0.75 0.2 0.70
CXCL6 0.1 0.2 0.0078 0.11 −0.8 0.022 0.5 0.20
CXCL8 3 40 0.0078 0.0078 −0.5 0.27 0.6 0.12
CXCL9 4 12 0.023 0.0078 0.7 0.046 −0.02 0.98
CXCL10 64 66 0.0078 0.0078 0.5 0.27 −0.05 0.93
CXCL11 0.4 31 >0.99 0.0078 0.1 0.75 0.1 0.79
CXCL12 0.9 0.6 0.84 0.055 0.5 0.24 −0.1 0.75
CXCL13 0.7 0.2 0.055 0.0078 0.8 0.037 0.1 0.79
CXCL16 0.7 0.7 0.20 0.023 −0.9 0.011 0.6 0.15
GM-CSF n/a n/a 0.039 0.55 0.2 0.66 0.5 0.17
IFN-γ n/a n/a 0.38 0.0078 −0.6 0.10 −0.1 0.84
IL-1β n/a n/a 0.0078 0.0078 −0.4 0.33 0.6 0.13
IL-2 n/a n/a 0.023 0.016 −0.6 0.10 −0.01 0.99
IL-4 n/a n/a 0.0078 0.0078 −0.6 0.12 0.5 0.27
IL-6 n/a n/a 0.078 0.0078 −0.7 0.058 0.4 0.28
IL-10 n/a n/a 0.055 0.64 −0.7 0.046 −0.1 0.88
IL-16 n/a n/a 0.31 0.15 −0.7 0.046 −0.1 0.79
MIF n/a n/a 0.25 0.016 0.2 0.66 −0.1 0.84
TNF-α n/a n/a 0.55 0.0078 −0.5 0.24 0.6 0.15