Fig. 3
From: Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats
Inhibition of heparanase attenuates leukocyte adhesion in pial venules induced by subarachnoid hemorrhage (SAH). a Representative images showed the effect of heparanase inhibition (via OGT2115) on SAH-associated pial venular leukocyte trafficking at 48 h post-SAH. The contour of the pial venules was observed under the bright field (upper panels). The leukocyte adhesion was expressed as the bright area occupied by Rhodamine-6G-labeled leukocytes (lower panels). Scale = 50 μm. b Quantitative results of the effects of heparanase inhibitor (OGT2115) on SAH associated pial venular leukocyte adhesion in SAH. Leukocyte adhesion is expressed as the percentage of the viewed venular area occupied by rhodamined-6G-labeled leukocytes. In b, values are mean ± SEM, n = 4–6 per group