Fig. 1
From: Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging
Hippocampal gene expression changes with aging. a Principle component analysis (PCA) of individual samples using all expressed genes. Groups separated by sex along the 1st component and by age in the 2nd component. b Heatmap presentation of all age-related gene expression differences. Samples were clustered (Euclidean distance) by sex and age. c Comparison of pairwise age-related changes in females. Total numbers of genes and direction of change (induction/reduction). For intersections patterns in respective groups are also noted. d Venn diagram of pairwise aging changes in males. e Comparison of age-related differences between males and females