Fig. 3
From: Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis
RNA sequencing analysis of isolated B cells from the spleens of MP4-immunized B6 mice that were treated with FTY720 (n = 5) or vehicle (n = 4), respectively, at the peak of EAE. Differential expression analysis results for B cell-related genes are shown. Log2 fold-changes of the comparison between vehicle- vs. drug-treated samples (n = 3 replicates each) calculated by DESeq2 for genes associated with BCR signaling in KEGG are plotted. Results with an adjusted p value below 0.05 are colored in orange while the remaining ones are colored in blue