Fig. 4

B cell subsets were measured by flow cytometry in the spleens of MP4-immunized mice that were treated at the peak of disease with 1 mg/kg BW FTY720 or vehicle, respectively. a Percentages of plasma cells and of B220⁺ B cells. b Percentages of the different B220⁺ B cell subsets. More detailed analysis of the percentages of c CD23⁺ regulatory B cells, d CD23⁻ regulatory B cells, e CD138⁺ memory B cells, and f CD138⁻ memory B cells. Bars show means ± SEM. *p < 0.05, Mann-Whitney test