Fig. 6
From: Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis
Histological analysis of B cell aggregates in the cerebella of MP4-immunized mice. a–d CD3/B220 double staining of representative cerebellar sections of a mouse treated with vehicle solution at the peak of disease. The panels demonstrate the different infiltrate categories. Bars represent 100 μm. e–g Quantification of the number of infiltrates per parenchymal area and distribution of infiltrate categories in mice treated either with 1 mg/kg BW FTY720 or vehicle at the peak of disease. h–j Quantification of the number of infiltrates per parenchymal area and distribution of infiltrate categories in mice treated 50 days after disease onset. Graphs show means ± SEM. *p < 0.05, **p < 0.01, Mann-Whitney test