Fig. 4

Neuro-2a cells modulate miRNA expression in response to IFN-γ treatment. a Neuro-2a cells treated with IFN-γ (100 units/ml) induced mmu-miR-322 and repressed mmu-miR-29a/b expression. b Stat1 knockdown using siRNA leads to upregulation of miR-29a/b. Neuro-2a cells were treated for 24 h with non-targeting siRNA or Stat1 siRNA. c Stat1 over-expression leads to decrease in miR-29a/b expression (n = 3; **p value ≤0.01)