Fig. 1
From: Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis
Long-term anticoagulation of SJL/J mice. PLP139–151-immunized mice were anticoagulated with warfarin via s.c. injections every 12 h during the course of the experiment. INR was measured on a regular basis (a). PLP139–151-immunized mice were anticoagulated with rivaroxaban. Rivaroxaban plasma concentration and thrombin activity in the plasma were measured on d15 and d27 post immunization (b, c)