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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Fig. 4

Preventive anticoagulation with warfarin and rivaroxaban decrease inflammatory lesions in the spinal cord of PLP139–151-immunized SJL/J mice. Representative images of DAPI stained lumbar spinal cord sections for the respective groups. Inflammatory lesions are marked by asterisk (ad, ×2.5 magnification, scale bar = 500 μm). Quantitative analysis of the cervical, thoracic, and lumbar spinal cord shows reduced inflammatory lesions on d15 and d27 after immunization in anticoagulated mice compared to controls (e, f)

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