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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Anticoagulation with warfarin and rivaroxaban ameliorates experimental autoimmune encephalomyelitis

Fig. 5

Thrombin increases brain endothelial permeability in vitro. PBMECs were seeded on transwell inserts and continuous TEER values were measured by a cellZscope® system. The graph displays a representative experiment that shows reduced TEER values of thrombin-treated PBMECs compared to control-treated ones (a). Quantification of brain endothelial permeability 1 h after thrombin treatment shows a decrease of TEER values in a dose-dependent manner. At least three replicates were averaged for one biological sample (n = 3, b)

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