Fig. 1

Details from the STRING interaction diagrams within the global transcriptome profiles of Pink1-deficient mouse cerebellar tissue. a At age 6 weeks, a network of splicing factors around Srsf10 was dysregulated. Red symbols indicate membrane-associated factors. The complete profile interaction diagram can be found in Additional file 2: Fig. S1A. b At age 18 months, a much denser network including inflammatory factors like Creb3, Irf3, Nfkbia, Mapk8, Mapk9, and Stat1 was dysregulated. Components of the “Toll-like receptor signaling pathway” factors are highlighted in red color. The complete profile interaction diagram can be found in Additional file 2: Fig. S1C