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Table 4 Immunoglobulin class response patterns

From: Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis

  Units Pattern I MS Pattern II + III MS Pattern II MS Pattern III MS AQP4-IgG+ NMO [48]
Three-class reaction Samples 0/16 (0) 0/32 (0) 0/21 (0) 0/11 (0) 0/87 (0%)
Two-class reaction Samples 2/16 (12.5) 2/32 (6.3) 2/21 (9.5) 0/11 (0) 5/87 (5.7%)
 IgG + IgM Samples 1 1 1 0 1/87 (1.1%)
 IgG + IgA Samples 1 1 1 0 1/87 (1.1%)
 IgM + IgA Samples 0 0 0 0 3/87 (3.4%)
One-class reaction Samples 5/16 (31.3) 6/32 (18.8) 6/21 (28.6) 0/11 (0) 13/87 (14.9%)
 Only IgG Samples 4 2 2 0 5/87 (5.7%)
 Only IgM Samples 1 4 4 0 7/87 (8%)
 Only IgA Samples 0 0 0 0 1/87 (1.1%)
  1. Concentrations, ratios and fractions are reported as medians; range and total sample numbers examined are given in brackets
  2. QIgG/A/M=CSF/serum IgG/A/M ratios