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Table 4 Immunoglobulin class response patterns

From: Pattern II and pattern III MS are entities distinct from pattern I MS: evidence from cerebrospinal fluid analysis

 

Units

Pattern I MS

Pattern II + III MS

Pattern II MS

Pattern III MS

AQP4-IgG+ NMO [48]

Three-class reaction

Samples

0/16 (0)

0/32 (0)

0/21 (0)

0/11 (0)

0/87 (0%)

Two-class reaction

Samples

2/16 (12.5)

2/32 (6.3)

2/21 (9.5)

0/11 (0)

5/87 (5.7%)

 IgG + IgM

Samples

1

1

1

0

1/87 (1.1%)

 IgG + IgA

Samples

1

1

1

0

1/87 (1.1%)

 IgM + IgA

Samples

0

0

0

0

3/87 (3.4%)

One-class reaction

Samples

5/16 (31.3)

6/32 (18.8)

6/21 (28.6)

0/11 (0)

13/87 (14.9%)

 Only IgG

Samples

4

2

2

0

5/87 (5.7%)

 Only IgM

Samples

1

4

4

0

7/87 (8%)

 Only IgA

Samples

0

0

0

0

1/87 (1.1%)

  1. Concentrations, ratios and fractions are reported as medians; range and total sample numbers examined are given in brackets
  2. QIgG/A/M=CSF/serum IgG/A/M ratios