| |
Units
|
Pattern I MS
|
Pattern II + III MS
|
Pattern II MS
|
Pattern III MS
|
AQP4-IgG+ NMO [48]
|
|---|
|
QAlb > Qlim(Alb)
|
Patients
|
4/10 (40)
|
15/22 (68.2)
|
9/15 (60)
|
6/7 (85.7)
|
n.d.
|
|
QAlb > Qlim(Alb)
|
Samples
|
4/17 (23.5)
|
30/43 (69.8)
|
16/26 (61.5)
|
14/17 (82.4)
|
75/147 (51%)
|
|
QAlb, all LPs
|
–
|
4.81 (3.01–10.8; 17)
|
8.39 (2.1–33.9; 42)
|
7.3 (2.1–33.9; 25)
|
9 (3.3–20.7; 17)
|
7 (2.3–57.1; 137)
|
|
QAlb, QAlb pos.
|
–
|
8.53 (6.3–10.8; 4)
|
9.8 (6.4–33.9; 29)
|
9 (6.4–33.9; 15)
|
10.25 (6.8––20.7; 14)
|
11.8 (5.63–57.14; 70)
|
|
Albumin CSF, all LPs
|
mg/L
|
204 (95–517; 17)
|
331 (81.2–726; 41)
|
255.5 (81.2–599; 24)
|
368 (137–726; 17)
|
284 (83.6–1890; 139)
|
|
Albumin CSF, QAlb pos.
|
mg/L
|
366 (251–517; 4)
|
371.5 (227–726; 28)
|
312 (227–599; 14)
|
431 (282–726; 14)
|
437 (219–1890)
|
|
Albumin serum, all LPs
|
g/L
|
40.6 (29.3–49.5; 17)
|
40 (22.6–51.8; 41)
|
39.85 (22.6–51.4; 24)
|
41.2 (32.7–51.8; 17)
|
40.7 (19.7–67.9; 133)
|
|
Albumin serum, QAlb pos.
|
g/L
|
43.15 (37.7–47.9; 4)
|
39.5 (22.6–50.9; 27)
|
35.55 (22.6–46.8; 14)
|
39.9 (32.7–50.9; 13)
|
39 (19.7–55.9)
|
|
Combined intrathecal IgG synthesis and disturbed blood–CSF barrier function
|
|
Patients, at least once
|
N (%)
|
3/10 (30)
|
4/20 (20)
|
3/13 (23.1)
|
1/7 (14.3)
|
n.d.
|
|
All LPs
|
N (%)
|
3/17 (17.6)
|
5/43 (11.6)
|
4/26 (15.4)
|
1/17 (5.9)
|
13/74 (17.6%)
|
-
n.d. no data
- QAlb = CSF/serum albumin ratio. Concentrations and ratios are reported as medians; range and total sample numbers examined are given in brackets
