Table 9 Summary of differences in CSF parameters between various MS subgroups as observed in the present study

CSF-restricted OCB, all LPs

Pattern I

15/17 (88.2)

P < 0.00004

Patterns II + III

10/37 (27)

Reiber et al. [19]

262/267 (98)

P < 0.000001

Patterns II + III

10/37 (27)

Pattern I

15/17 (88.2)

P < 0.0001

Pattern II

9/25 (36)

Pattern III

1/12 (8.3)

CSF-restricted OCB, patients

Pattern I

8/10 (80)

P < 0.03

Patterns II + III

7/22 (31.8)

Reiber et al. [19]

262/267 (98)

P < 0.000001

Patterns II + III

7/22 (31.8)

CSF-restricted OCB, patients, w/o transient OCBs

Pattern I

8/10 (80)

P < 0.006

Patterns II + III

5/22 (22.7)

Reiber et al. [19]

262/267 (98)

P < 0.00001

Patterns II + III

5/22 (22.7)

MRZ reaction (≥2 AIs >1.5), all LPs

Jarius et al. [23]

397/546 (69)

P < 0.000001

Patterns II + III

0/12 (0)

M and/or R and/or Z >1.5, all LPs

Reiber et al. [19]

158/177 (89)

P < 0.000001

Patterns II + III

0/12 (0)

QIgG > Q_lim(lgG), all LPs

Pattern I

7/17 (41.2)

P < 0.03

Patterns II + III

5/41 (12.2)

QAlb > Q_lim(Alb), all LPs

Pattern I

4/17 (23.5)

P < 0.002

Patterns II + III

30/43 (69.8)

Pattern I

4/17 (23.5)

P = 0.002

Pattern II

16/26 (61.5)

Pattern III

14/17 (82.4)

QAlb, all LPs

Pattern I

4.81 (3.01–10.8; 17)

P < 0.005

Patterns II + III

8.39 (2.1–33.9; 42)

Albumin CSF, all LPs

Pattern I

204 (95–517; 17)

P < 0.009

Patterns II + III

331 (81.2–726; 41)

Total CSF protein elevated, all LPs

Pattern I

3/15 (20)

P < 0.003

Patterns II + III

29/43 (67.4)

Total CSF protein, all LPs

Pattern I

375 (187–750; 15)

P < 0.007

Patterns II + III

550 (168–1930; 43)

Albuminocytological dissociation, all LPs

Pattern I

1/8 (12.5)

P < 0.04

Patterns II + III

13/21 (61.9)