Fig. 8From: Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitisBDNF reduces hippocampal apoptosis in PM. Apoptotic neurons in the hippocampal dentate gyrus were assessed by TUNEL staining. a BDNF administration prevented neurons from apoptotic injury from PM-induced hippocampal apoptosis, whereas k252a-pretreatment significantly elevated levels of hippocampal apoptosis as compared with levels observed in the BDNF + PM group. b Quantitative analysis of the TUNEL results. **p < 0.01Back to article page