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Table 1 Bacterial titer, change of weight, neurological scores, and mortality in different groups (mean ± standard deviation)

From: Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis

Groups

Bacterial titer, 24 hpi [log10 CFU mL−1]

Change of weight

Neurological scoresa

Mortality

Sham

–

−2.64 ± 0.46

5 [5, 5]

0/10

PBS + PM

7.97 ± 0.50

1.50 ± 0.39*

3 [3, 4]*

4/14

DMSO + PM

7.87 ± 0.42

1.37 ± 0.45*

3 [3, 4]*

3/14

BDNF + PM

7.35 ± 0.41**

1.08 ± 0.36*,**

4 [3, 4]*, **

2/14

k252a + PM

8.08 ± 0.27***

2.28 ± 1.40*, ***

3 [3, 4]*, ***

5/14

  1. Bacterial titer, change of weight, neurological scores, and mortality were evaluated at 24 h post-infection
  2. *p < 0.05, compared to sham group
  3. **p < 0.05, compared to PBS + PM group
  4. ***p < 0.05, compared to BDNF + PM group
  5. aMedian [minimum, maximum]
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Journal of Neuroinflammation

ISSN: 1742-2094