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Table 4 Comparative gene fold changes by age group for significantly impacted genes

From: Age exacerbates microglial activation, oxidative stress, inflammatory and NOX2 gene expression, and delays functional recovery in a middle-aged rodent model of spinal cord injury

Comparative fold change by age group
3 months old Gene tested 12 months old
Naïve 30 dpi Naïve 30 dpi
1.467 ± 0.8292 4.481 ± 1.179 CD86 0.6781 ± 0.3546 0.7444 ± 0.08664
1.731 ± 0.5850 0.7586 ± 0.5561 CD206 1.094 ± 0.3027 111,858 ± 67,300
1.043 ± 0.2966 225.2 ± 76.85 p22PHOX 1.005 ± 0.06771 218.9 ± 132.1
1.491 ± 0.8159 3.134 ± 2.551 p47PHOX 1.232 ± 0.4360 *180,416 ± 31,468
1.001 ± 0.02864 28.02 ± 3.662 gp91PHOX 1.154 ± 0.3588 *54.89 ± 21.85
  1. Table demonstrates the effect of injury on gene expression within age groups. The average of the naïve in both the 3- and 12-month-age groups was considered the control mean value. Each individual sample’s fold change was compared to the control mean. Fold changes are presented in the table as mean values of all samples in each group ± SEM. N = 4/group
  2. *p < 0.005