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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease

Fig. 3

At time 0, CSF NGAL, IFNγ, CRP, and serum CRP disease-dependently covary with Aβs. PD subjects demonstrate a relationship between CSF NGAL and CSF α-synuclein (a; F(1,10) = 11.73; p = 0.007) as well as CSF NGAL and CSF Aβ40 (b; F(1,10) = 5.86; p = 0.04), while HC subjects do not. HC subjects demonstrate a relationship between CSF IFNγ and CSF α-synuclein (c; F(1,4) = 18.88; p = 0.01), CSF CRP and Aβ40 (d; F(1,4) = 8.03; p = 0.05), and serum CRP and Aβ40 (e; F(1,4) = 8.80; p = 0.04), while PD subjects do not (see Additional file 7 for all correlation data). * indicates p < 0.05 and ** indicates p < 0.01

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