Table 4 Blood-associated microRNAs as diagnostic markers in autism and schizophrenia
Disease | Samples | microRNAs | Reference | ||
|---|---|---|---|---|---|
Type | Number | Downregulated | Upregulated | ||
Autism | Serum | 55 patients; 55 controls | miR-151a-3p, miR-181b-5p, miR-320a, miR-328, miR-433, miR-489, miR-572, miR-663a | miR-101–3p, miR-106b-5p, miR-130a-3p, miR-195-5p, miR-19b-3p | Mundalil Vasu et al. 2014 |
Peripheral blood | 20 patients; 20 controls | let-7a, let-7d, miR-103a, miR-1228 | miR-34b | Huang et al. 2015 | |
Schizophrenia | Plasma | 564 patients; 400 controls | NF | miR-130b, miR-193a-3p | Wei et al. 2015 |
PBMC | 90 patients; 60 controls | miR-432 | miR-34a, miR-449a, miR-564, miR-548d, miR-572, miR-652 | Lai et al. 2011 | |
Plasma | 50 patients; 50 controls | NF | miR-7 | Zhang et al. 2015 | |
Plasma and PBMC | 25 patients; 13 controls | NF | miR-132, miR-195, miR-30e, miR-7 in plasma; miR-212, miR-34a, miR-30e in PBMC | Sun, Lu et al. 2015a | |
Plasma | 61 patients; 62 controls | NF | miR-181b, miR-30e, miR-346, miR-34a, miR-7 | Sun, Zhang et al. 2015b | |
Serum | 145 patients; 40 controls | miR-195, miR-17 | miR-181b, miR-219-2-3p, miR-1308, let-7g, miR-346, miR-92a | Shi et al., 2012 | |
Plasma | 20 patients; 20 controls | NF | miRNA-181b, miRNA-30e, miRNA-34a, miRNA-7 | Song et al. 2014a | |