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Table 4 Blood-associated microRNAs as diagnostic markers in autism and schizophrenia

From: Bridging Autism Spectrum Disorders and Schizophrenia through inflammation and biomarkers - pre-clinical and clinical investigations

Disease Samples microRNAs Reference
Type Number Downregulated Upregulated
Autism Serum 55 patients; 55 controls miR-151a-3p, miR-181b-5p, miR-320a, miR-328, miR-433, miR-489, miR-572, miR-663a miR-101–3p, miR-106b-5p, miR-130a-3p, miR-195-5p, miR-19b-3p Mundalil Vasu et al. 2014
Peripheral blood 20 patients; 20 controls let-7a, let-7d, miR-103a, miR-1228 miR-34b Huang et al. 2015
Schizophrenia Plasma 564 patients; 400 controls NF miR-130b, miR-193a-3p Wei et al. 2015
PBMC 90 patients; 60 controls miR-432 miR-34a, miR-449a, miR-564, miR-548d, miR-572, miR-652 Lai et al. 2011
Plasma 50 patients; 50 controls NF miR-7 Zhang et al. 2015
Plasma and PBMC 25 patients; 13 controls NF miR-132, miR-195, miR-30e, miR-7 in plasma; miR-212, miR-34a, miR-30e in PBMC Sun, Lu et al. 2015a
Plasma 61 patients; 62 controls NF miR-181b, miR-30e, miR-346, miR-34a, miR-7 Sun, Zhang et al. 2015b
Serum 145 patients; 40 controls miR-195, miR-17 miR-181b, miR-219-2-3p, miR-1308, let-7g, miR-346, miR-92a Shi et al., 2012
Plasma 20 patients; 20 controls NF miRNA-181b, miRNA-30e, miRNA-34a, miRNA-7 Song et al. 2014a
  1. NF not found, PBMC peripheral blood mononuclear cells